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Lab-Grown Blood Stem Cells Produced at Last

After 20 years of trying, scientists have transformed mature cells into primordial blood cells that regenerate themselves and the components of blood. The work, described today in Nature, offers hope to people with leukaemia and other blood disorders who need bone-marrow transplants but can’t find a compatible donor. If the findings translate into the clinic, these patients could receive lab-grown versions of their own healthy cells. One team, led by stem-cell biologist George Daley of Boston Children’s Hospital in Massachusetts, created human cells that act like blood stem cells, although they are not identical to those found in nature. A second team, led by stem-cell biologist Shahin Rafii of Weill Cornell Medical College in New York City, turned mature cells from mice into fully fledged blood stem cells. “For many years, people have figured out parts of this recipe, but they’ve never quite gotten there,” says Mick Bhatia, a stem-cell researcher at McMaster University i...

Mesentery: New organ discovered inside human body by scientists

A new organ has been discovered hiding in plain sight inside the human body . Known as the mesentery, it was previously thought to be just a few fragmented structures in the digestive system. But scientists have realised it is in fact one, continuous organ. Although its function is still unclear, the discovery opens up “a whole new area of science,” according to J Calvin Coffey, a researcher at the University Hospital Limerick who first discovered it. "When we approach it like every other organ… we can categorise abdominal disease in terms of this organ," he said. “Now we have established anatomy and the structure. The next step is the function. If you understand the function you can identify abnormal function, and then you have disease. “Put them all together and you have the field of mesenteric science.” The research has been published in The Lancet medical journa...

US Moves to Shut Down 2 Big Stem Cell Therapy Clinics

Federal authorities Wednesday moved to shut down two of the country’s most prominent for-profit providers of stem cell therapy, one of them a network of clinics with more than 100 offices in the United States, including several in the Bay Area. The Food and Drug Administration filed two complaints in federal court requesting permanent injunctions that would stop Florida-based U.S. Stem Cell Clinic and the California Stem Cell Treatment Center from marketing therapies. Both companies have previously been called out by the FDA for providing unproven, unapproved therapies that could put patients at risk. The injunction requests are an aggressive move by the FDA to patrol the consumer stem cell market. The agency has come under mounting pressure by scientists and patient advocates to increase oversight of the growing consumer market, which has been allowed to flourish for years. “In the two cases filed today, the clinics and their leadership have continued to disregard th...

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