Stem Cells Therapy in India

A gene known to suppress tumor formation in a broad range of tissues plays a key role in keeping stem cells in muscles dormant until needed, a finding that may have implications for both human health and animal production, according to a Purdue University study. Shihuan Kuang, professor of animal sciences, and Feng Yue, a postdoctoral researcher in Kuang’s lab, reported their findings in two papers published in the journals Cell Reports and Nature Communications. The results suggest modifying expression of the PTEN gene could one day play a role in increasing muscle mass in agricultural animals and improve therapies for muscle injuries in humans. Muscle stem cells, called satellite cells, normally sit in a quiescent, or dormant, state until called upon to build muscle or repair a damaged muscle. Inability to maintain the quiescence would lead to a loss of satellite cells. As humans age, the number of satellite cells gradually declines and the remaining cells become less effective...

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers. "In 2012, we discovered that if we treated human stem cells with chemicals that sequentially activate and inhibit Wnt signaling pathway, they become myocardium muscle cells," said Xiaojun Lance Lian, assistant professor of biomedical engineering and biology, who is leading the study at Penn State. Myocardium, the middle of the heart's three layers, is the thick, muscular part that contracts to drive blood through the body. The Wnt signaling pathway is a group of signal transduction pathways made of proteins that pass signals into a cell using cell-surface receptors. "We needed to provide the cardiac progenitor cells with additional information in order for them to generate into epicardium cells, but prior to this study, we didn't know what that information was," said Lia...

Another breakthrough awaits human kind as Stanford health physicians take on a new challenge and research trial on stem cell therapy. Stem cells that are derived from fat tissue will be tested and checked if it can work as an alternative to surgery. This cell trial is approved by the Food and Drug Administration agency. It is the first to involve fat-derived stem cells. It works by using a liposuction to extract the fat tissue from the abdomen. The fat tissues will then be treated with a special enzyme and will be subjected to centrifuge to separate the stem cells. The clinical trial will involve the body's natural healing process to heal shoulder injuries. Some people sometimes refer to shoulder concerns as a tooth ache which is likened to a dull pain that seems to stay. It is known that when a person reaches 45, the tendons go through a wear and tear process that causes small tears causing the pain as per KDLT News. Adult stem cells will be used and not embryonic s...

A new organ has been discovered hiding in plain sight inside the  human body . Known as the mesentery, it was previously thought to be just a few fragmented structures in the digestive system. But scientists have realised it is in fact one, continuous organ.  Although its function is still unclear, the discovery opens up “a whole new area of science,” according to J Calvin Coffey, a researcher at the  University Hospital Limerick  who first discovered it.  "When we approach it like every other organ… we can categorise abdominal disease in terms of this organ," he said.   “Now we have established anatomy and the structure. The next step is the function. If you understand the function you can identify abnormal function, and then you have disease.  “Put them all together and you have the field of mesenteric science.” The research has been published in  The Lancet   medical journa...

Researchers are developing a spider silk that has antimicrobial properties, for use with regenerative medicine, wound healing and for drug delivery. The discovery came about after a chance meeting between an expert on arachnids and a chemist. This meeting led to five years of development work conducted by the University of Nottingham. The outcome of this has been to fashion a method that produces chemically functionalised spider silk. The silk can be used for a range of applications including drug delivery, regenerative medicine and wound healing. The silk is created by a bacterium via recombinant technology. With this the artificially produced spider silk is synthesised by Escherichia coli bacteria.  The reason for using a variant of silk is because it is very strong and it is also biocompatible and biodegradable. In addition, the material does not adversely react with the human body and no immune response is triggered. The basis of this is something called 'click-...

Baltimore is home to world class doctors and medical teams who work miracles each day. The University of Maryland Medical Center is trying a brand new procedure to treat the tiniest heart patients.  They're using stem cells to help babies born with heart defects. Dr. Sunjay Kaushal is the pediatric cardiac surgeon pioneering the new treatment to save the littlest lives.  Source: https://goo.gl/445nlN