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Showing posts from 2017

Lab-Grown Blood Stem Cells Produced at Last

After 20 years of trying, scientists have transformed mature cells into primordial blood cells that regenerate themselves and the components of blood. The work, described today in Nature, offers hope to people with leukaemia and other blood disorders who need bone-marrow transplants but can’t find a compatible donor. If the findings translate into the clinic, these patients could receive lab-grown versions of their own healthy cells. One team, led by stem-cell biologist George Daley of Boston Children’s Hospital in Massachusetts, created human cells that act like blood stem cells, although they are not identical to those found in nature. A second team, led by stem-cell biologist Shahin Rafii of Weill Cornell Medical College in New York City, turned mature cells from mice into fully fledged blood stem cells. “For many years, people have figured out parts of this recipe, but they’ve never quite gotten there,” says Mick Bhatia, a stem-cell researcher at McMaster University i...

Stem Cell Therapy Shows Potential in Treating Medication-Resistant Epilepsy Patients

Stem cell therapy may be a safe and promising treatment option for epilepsy patients who are resistant to antiepileptic drugs, according to new research. Stem cell therapy consists of using stem cells (immature cells that can become any other cell type in the body) to replace faulty cells and treat patients with a given disease. Many approaches include using the patient’s own stem cells (autologous stem cells), collected from specific organs, such as the bone marrow. This method prevents future complications such as rejection by the body or a response from the person’s immune system. “Autologous patient-derived [stem cells] represent a stem cell population easy to isolate and expand without ethical or technological limitations,” researchers from the Republic of Belarus wrote. The Phase 1 trial (NCT02497443) investigated the safety of treating treatment-resistant epilepsy patients with stem cell therapy. Patients received either standard treatment with anti-epileptic drugs...

I OWE MY YOUNGER LOOK AND GREAT SKIN TO GIOSTAR

Everyone wants to look younger and so do I, and when I came to know how Stem Cell Treatment helps in rejuvenating and repairing damaged organs and tissues, which include our skin, I was simply blown off. Of late scientists have discovered the fact that non-embryonic cells, which are extracted from humans can aid in fighting age spots, wrinkles, and even fine lines. There was still a lot of doubt about the treatment’s effectiveness in my mind, so I approached Giostar. There I realized that how this therapy actually fights aging.  I am a public figure, so I am always concerned with my looks, and wrinkles and fine lines are a definite setback for me. This is why I decided to go through this therapy, but only under expert supervision. I compared many centers offering such treatments, but Giostar Reviews impressed me the most. This is when I decided that Giostar is the place to be, because it has pioneered Stem Cell Treatment in India, and positive Giostar Reviews shows it as ...

Risks of Unproven Stem Cell Treatments

An expert in stem cell treatment is warning of dodgy operators in New Zealand offering unproven and potentially dangerous treatments. Auckland University Medical School lecturer Bronwen Connor's warning comes after a recently-released scientific paper documented a case of three women in the United States who were blinded by an experimental treatment for macular degeneration.  She said many people had stem cell therapy in the belief it was scientifically valid, but that was not often the case. Dr Connor told Nine To Noon the cells used most often for the treatments were known as adipose cells, which were obtained from fat tissue in the body. They were popular because they could be obtained from a patient by liposuction, isolated out, then re-injected for supposed therapeutic use. "Adipose stem cells obviously have a very important job, but predominantly their job is to make bone and cartilage. They also do have some anti-inflammatory properties. But they, ...

A Japanese Man Just Got Another Person's Stem Cells Transplanted in His Eye

In what's reported to be a world-first, last Tuesday, a Japanese man received a pioneering retinal cell transplant grown from donor stem cells instead of his own. Doctors took skin cells from a donor bank and reprogrammed them into induced pluripotent stem (iPS) cells, which can be coaxed to grow into most cell types in the body. For this procedure, the physicians grew the iPS cells into a type of retinal cell, and then injected them into the retina of the patient's right eye. The test subject was a man in his 60s who has been living with age-related macular degeneration - a currently incurable eye disease that slowly leads to loss of vision. If this news sounds somewhat familiar, it's because the same team of Japanese doctors successfully performed a similar transplant in 2014. But in that case, the iPS cells came from the patient's own skin, not from a donor. The 2014 treatment involved culturing a patient's cells into a thin sheet of...

Tumor suppressor key in maintaining stem cell status in muscle

A gene known to suppress tumor formation in a broad range of tissues plays a key role in keeping stem cells in muscles dormant until needed, a finding that may have implications for both human health and animal production, according to a Purdue University study. Shihuan Kuang, professor of animal sciences, and Feng Yue, a postdoctoral researcher in Kuang’s lab, reported their findings in two papers published in the journals Cell Reports and Nature Communications. The results suggest modifying expression of the PTEN gene could one day play a role in increasing muscle mass in agricultural animals and improve therapies for muscle injuries in humans. Muscle stem cells, called satellite cells, normally sit in a quiescent, or dormant, state until called upon to build muscle or repair a damaged muscle. Inability to maintain the quiescence would lead to a loss of satellite cells. As humans age, the number of satellite cells gradually declines and the remaining cells become less effective...

Stem cells used to regenerate the external layer of a human heart

A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers. "In 2012, we discovered that if we treated human stem cells with chemicals that sequentially activate and inhibit Wnt signaling pathway, they become myocardium muscle cells," said Xiaojun Lance Lian, assistant professor of biomedical engineering and biology, who is leading the study at Penn State. Myocardium, the middle of the heart's three layers, is the thick, muscular part that contracts to drive blood through the body. The Wnt signaling pathway is a group of signal transduction pathways made of proteins that pass signals into a cell using cell-surface receptors. "We needed to provide the cardiac progenitor cells with additional information in order for them to generate into epicardium cells, but prior to this study, we didn't know what that information was," said Lia...

ReNeuron says stem cells improved motor function in stroke study

Another breakthrough awaits human kind as Stanford health physicians take on a new challenge and research trial on stem cell therapy. Stem cells that are derived from fat tissue will be tested and checked if it can work as an alternative to surgery. This cell trial is approved by the Food and Drug Administration agency. It is the first to involve fat-derived stem cells. It works by using a liposuction to extract the fat tissue from the abdomen. The fat tissues will then be treated with a special enzyme and will be subjected to centrifuge to separate the stem cells. The clinical trial will involve the body's natural healing process to heal shoulder injuries. Some people sometimes refer to shoulder concerns as a tooth ache which is likened to a dull pain that seems to stay. It is known that when a person reaches 45, the tendons go through a wear and tear process that causes small tears causing the pain as per KDLT News. Adult stem cells will be used and not embryonic s...

Mesentery: New organ discovered inside human body by scientists

A new organ has been discovered hiding in plain sight inside the  human body . Known as the mesentery, it was previously thought to be just a few fragmented structures in the digestive system. But scientists have realised it is in fact one, continuous organ.  Although its function is still unclear, the discovery opens up “a whole new area of science,” according to J Calvin Coffey, a researcher at the  University Hospital Limerick  who first discovered it.  "When we approach it like every other organ… we can categorise abdominal disease in terms of this organ," he said.   “Now we have established anatomy and the structure. The next step is the function. If you understand the function you can identify abnormal function, and then you have disease.  “Put them all together and you have the field of mesenteric science.” The research has been published in  The Lancet   medical journa...

Antibiotic spider silk promises improved drug delivery

Researchers are developing a spider silk that has antimicrobial properties, for use with regenerative medicine, wound healing and for drug delivery. The discovery came about after a chance meeting between an expert on arachnids and a chemist. This meeting led to five years of development work conducted by the University of Nottingham. The outcome of this has been to fashion a method that produces chemically functionalised spider silk. The silk can be used for a range of applications including drug delivery, regenerative medicine and wound healing. The silk is created by a bacterium via recombinant technology. With this the artificially produced spider silk is synthesised by Escherichia coli bacteria.  The reason for using a variant of silk is because it is very strong and it is also biocompatible and biodegradable. In addition, the material does not adversely react with the human body and no immune response is triggered. The basis of this is something called 'click-...

Stem cell injections used to help babies born with heart defects

Baltimore is home to world class doctors and medical teams who work miracles each day. The University of Maryland Medical Center is trying a brand new procedure to treat the tiniest heart patients.  They're using stem cells to help babies born with heart defects. Dr. Sunjay Kaushal is the pediatric cardiac surgeon pioneering the new treatment to save the littlest lives.  Source: https://goo.gl/445nlN