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Showing posts from May, 2017

Lab-Grown Blood Stem Cells Produced at Last

After 20 years of trying, scientists have transformed mature cells into primordial blood cells that regenerate themselves and the components of blood. The work, described today in Nature, offers hope to people with leukaemia and other blood disorders who need bone-marrow transplants but can’t find a compatible donor. If the findings translate into the clinic, these patients could receive lab-grown versions of their own healthy cells. One team, led by stem-cell biologist George Daley of Boston Children’s Hospital in Massachusetts, created human cells that act like blood stem cells, although they are not identical to those found in nature. A second team, led by stem-cell biologist Shahin Rafii of Weill Cornell Medical College in New York City, turned mature cells from mice into fully fledged blood stem cells. “For many years, people have figured out parts of this recipe, but they’ve never quite gotten there,” says Mick Bhatia, a stem-cell researcher at McMaster University i...

Stem Cell Therapy Shows Potential in Treating Medication-Resistant Epilepsy Patients

Stem cell therapy may be a safe and promising treatment option for epilepsy patients who are resistant to antiepileptic drugs, according to new research. Stem cell therapy consists of using stem cells (immature cells that can become any other cell type in the body) to replace faulty cells and treat patients with a given disease. Many approaches include using the patient’s own stem cells (autologous stem cells), collected from specific organs, such as the bone marrow. This method prevents future complications such as rejection by the body or a response from the person’s immune system. “Autologous patient-derived [stem cells] represent a stem cell population easy to isolate and expand without ethical or technological limitations,” researchers from the Republic of Belarus wrote. The Phase 1 trial (NCT02497443) investigated the safety of treating treatment-resistant epilepsy patients with stem cell therapy. Patients received either standard treatment with anti-epileptic drugs...