Exploiting stem cells for their restorative properties is the primary underlying goal of regenerative medicine. Now, researchers at Johns Hopkins have identified a protein that plays a vital role in the lives of stem cells, which they believe can bolster the growth of damaged muscle tissue. The results from this new study could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy. The findings, published recently in Nature Medicine in an article entitled “Targeting β1-Integrin Signaling Enhances Regeneration in Aged and Dystrophic Muscle in Mice,” showed that the presence of the β1-integrin protein helped promote the transformation of undifferentiated stem cells into muscle after the tissue had degraded and improve regenerated muscle fiber growth as much as 50%. While the presence of β1-integrin in adult stem cells is ostensible, the precise molecular mechanism it employs within these cells has not been examined...