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Showing posts from May, 2015

Stem Cells Signal Mouse's Own Cells To Mend The Fracture

Treatment with bone marrow-derived stem cells could prove to be an effective strategy for slow healing bone fractures in diabetics, a pre-clinical study suggested. When nondiabetic human bone marrow-derived mesenchymal stem cells (hMSCs) were administered directly to femur fractures in a murine model of diabetes, the bones healed more efficiently than nontreated bone, reported Cynthia Coleman, PhD, of the National University of Ireland in Galway, and colleagues. he stem-cell treated bones were also significantly stronger than nontreated bone, they stated in a report at the 2015 European Congress of Endocrinology (ECE) meeting. Both the metabolic and endocrine impact of diabetes can adversely affect bone quality and may increase fracture risk. Lower bone mass and increased fracture risk have long been recognized as a complication of type 1 diabetes, and fracture is also increasingly recognized as a concern for patients with type 2 diabetes, despite their often higher, obes...